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Food and Drug Administration (FDA) Endocrinologic and Metabolic Drugs Advisory Committee did not recommend approval of rimonabant (Zimulti / Accomplia) to the US FDA. Rimonabant is not yet accustomed for use in the United States, area it is accepted as Zimulti. 15 -- People who take the weight-loss drug rimonabant may face heightened risks for severe depression and anxiety, Danish researchers report. Effect of Rimonabant on Body Weight and the Metabolic Syndrome in Overweight Patients. Acomplia (rimonabant) is the aboriginal in a new chic of ameliorative agents alleged Cannabinoid-1 Receptor Blockers (CB1). The undeclared active pharmaceutical ingredients in some of these products include sibutramine (a controlled substance), rimonabant ( a drug not approved for marketing in the United States), phenytoin ( an anti-seizure medication), and phenolphthalein (a solution used in chemical experiments and a suspected cancer causing agent).

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