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The safety of Ditropan administered to women who are or who may become pregnant has not been established. html"Ditropan should be used with caution in patients with preexisting dementia treated with cholinesterase inhibitors (eg Aricept, Reminyl, Exelon) due to the risk of aggravation of symptoms. Ditropan is also used to treat the urgency, frequency, leakage, incontinence, and painful or difficult urination caused by a neurogenic bladder (altered bladder function due to a nervous system abnormality). It is especially important to check with your doctor before combining Ditropan with alcohol or sedatives such as temazepam or triazolam because increased drowsiness may occur. When all available data are normalized to an equivalent of 5 mg twice daily Ditropan, the mean pharmacokinetic parameters derived for R- and S-oxybutynin and R- and S-desethyloxybutynin are summarized in Table 2a (for tablet) and Table 2b (for syrup). Ditropan should also be avoided if you have severe colitis (inflamed colon), myasthenia gravis (abnormal muscle weakness), or urinary tract obstruction (inability to urinate).
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