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If chloroquine hydrochloride injection is given intravenously in pediatric patients, it should be diluted and administered very slowly. Children who cannot take mefloquine or doxycycline can be given chloroquine for prophylaxis in chloroquine-sensitive areas {31} {41}. Chloroquine also is taken up into the acidic food vacuoles of the parasite in the erythrocyte. Epinephrine has been shown to decrease the myocardial depressant and vasodilatory effects of chloroquine {19} {20}. 4 mg (base) per kg per day of chloroquine {03}.
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